Although hypoxia is often pathologic, chronic continuous hypoxia has shown promise in many disease models, inspiring a roadmap for clinical translation.

Evidence from patients and pigs with cystic fibrosis suggests pathological changes in leukocytes are present from birth.

Combining transient mixed chimerism with kidney cotransplantation achieves heart allograft tolerance in nonhuman primates.

Aβ induces neuronal hyperconnectivity, which promotes tau spreading from temporal lobe epicenters to connected brain regions in Alzheimer’s disease.

Targeting integrins relieves on-target, off-tumor toxicity of CAR-T cells while preserving their antitumor efficacy.

When it comes to sending humans back to the moon, knowing how to work with the regolith that coats the ground will be make-or-break. Phil Metzger is studying how to mitigate its dangers and use it as a crucial resource

James Temple was "in the right place at the right time" to take these dramatic images of SpaceX's Starship's seventh flight test disintegrating above the Atlantic Ocean

Observations of WASP-127b, a giant gas exoplanet more than 500 light years from Earth, suggest it has phenomenally high wind speeds

After a close look with a powerful radio telescope, astronomers are still puzzled by a pair of objects with strange characteristics first spotted in 2021

All seven of the other planets in our solar system are about to become visible at once in a great planetary alignment – here’s how to spot the celestial show

A man with paralysis was able to fly a virtual drone through a complex obstacle course simply by thinking about moving his fingers, with signals being interpreted by an AI model

A flying robot the size of a postage stamp can hover for up to 15 minutes without breaking, and it can perform acrobatic manoeuvres

Now that the US Supreme Court has decided that a law banning TikTok is constitutional, the platform is set to shut down in the US on 19 January – but Trump could still save it

ELIZA is famous as a rudimentary artificial intelligence and the first ever chatbot, but versions found online today are actually knock-offs because the original computer code was lost – until now

Blue Origin and SpaceX both launched rockets on 16 January, but while Jeff Bezos's company saw a launch success with New Glenn, Elon Musk's Starship exploded. What does this mean for the future of the space industry?

Trained pianists who hit a plateau improved their finger speed after a half-hour training session with a device that moves their fingers for them

In the opening to Adrian Tchaikovsky's science fiction novel Alien Clay, the latest read for the New Scientist Book Club, our hero wakes from years of space travel to a terrifying new reality

As apparent acts of sabotage cut undersea data cables around the world, NATO held its first demonstration of a project to quickly reroute crucial communications to satellite internet

NASA's former chief scientist, Jim Green, explains how close we are to having humans on Mars

After delays and false starts, Jeff Bezos's firm Blue Origin has reached orbit with its first launch of the New Glenn rocket, though attempts to land the first stage at sea were unsuccessful