Science
This book is a great insight into the new science of microchimerism
Lise Barnéoud's Hidden Guests shows how this fascinating new field brings with it profound implications for medicine, and even what it means to be human, finds Helen Thomson
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Human minds abhor uncertainty. This is a problem for liberal democracy
Neurologically, the flexibility of the future promised by liberal democracy can be a challenge because it brings with it uncertainty. But there are solutions, say Florence Gaub and Liya Yu
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Deep-space sci-fi novel is delightful, profound and not to be missed
A planet is about to be destroyed by the collapse of a binary star system in Slow Gods, Claire North’s first venture into classic science fiction. Read it! says Emily H. Wilson
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Lumpy ‘caterpillar wormholes’ may connect entangled black holes
A mathematical model suggests that when a pair of black holes gets quantum entangled, this can give rise to a lumpy space-time tunnel between them
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Lumpy ‘caterpillar wormholes’ may connect entangled black holes
A mathematical model suggests that when a pair of black holes gets quantum entangled, this can give rise to a lumpy space-time tunnel between them
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What we’re learning about consciousness from master meditators’ brains
Neuroscientist Matthew Sacchet is revealing how mastering meditation can not only enable transcendental states of bliss, but also reshape how we experience pain and emotion
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What we’re learning about consciousness from master meditators’ brains
Neuroscientist Matthew Sacchet is revealing how mastering meditation can not only enable transcendental states of bliss, but also reshape how we experience pain and emotion
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Beyond Alzheimer’s disease—translating biomarker insights across CNS diseases | Science Translational Medicine
Lessons learned from Alzheimer’s disease biomarker history can advance diagnostics and disease staging for other central nervous system disorders.
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The m6A demethylase FTO links TLR7 to mitochondrial oxidation driving age-associated B cell formation in systemic lupus erythematosus | Science Translational Medicine
TLR7 drives age-associated B cell formation in lupus through m6A demethylase FTO-mediated mitochondrial oxidation.
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Depletion of plasmacytoid dendritic cells rescues HIV-reactive stem-like CD8+ T cells during chronic HIV-1 infection | Science Translational Medicine
Plasmacytoid dendritic cells impair HIV-reactive CD8+ T cells in HIV-infected humanized mice and in PBMCs from people living with HIV.
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Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens | Science Translational Medicine
MHC class II immunopeptidomics in human phagocytes infected with Mycobacterium tuberculosis enables vaccine immunogen design and optimization.
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A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology | Science Translational Medicine
Multiplexed imaging of aGVHD GI biopsies revealed epithelial remodeling and alteration in immune composition, offering insight into disease pathology.
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Burst-patterned stimulation restores colonic motility in preclinical models | Science Translational Medicine
Distinct temporal patterns of electrical stimulation of the sacral nerves selectively regulate colonic motility.
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DLL1-responsive PD-L1+ tumor-associated macrophages promote endocrine resistance in breast cancer | Science Translational Medicine
Triple combination therapy reverses endocrine resistance driven by DLL1high tumor cells, which recruit immunosuppressive PD-L1+ TAMs sustaining CSCs.
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Toxic algae blighting South Australia could pose a global threat
Researchers warn that the alga Karenia cristata, which has killed around a million animals in Australian waters in one of the biggest algal blooms ever seen, could harm marine life elsewhere
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Toxic algae blighting South Australia could pose a global threat
Researchers warn that the alga Karenia cristata, which has killed around a million animals in Australian waters in one of the biggest algal blooms ever seen, could harm marine life elsewhere
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Ancient DNA may rewrite the story of Iceland's earliest settlers
Biochemical evidence suggests Norse people settled in Iceland almost 70 years before the accepted arrival date of the 870s, and didn't chop down the island's forests
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Ancient DNA may rewrite the story of Iceland's earliest settlers
Biochemical evidence suggests Norse people settled in Iceland almost 70 years before the accepted arrival date of the 870s, and didn't chop down the island's forests
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COP30: What’s on the agenda at the Belém climate summit
Initiatives on the table at COP30 aim to evaluate which countries are most vulnerable, support efforts to clean up industries and pay for the protection of tropical forests
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COP30: What’s on the agenda at the Belém climate summit
Initiatives on the table at COP30 aim to evaluate which countries are most vulnerable, support efforts to clean up industries and pay for the protection of tropical forests
Categories: Science