Itepekimab and dupilumab modulate both distinct and common inflammatory mediators in mouse models of airway inflammation and in humans with asthma.

Depletion of the ER stress sensor IRE1α can reduce paclitaxel-induced peripheral neuropathy in mice.

Lymphotoxin-α release from B cells impairs neuronal activity in coculture models, which is reversible upon BTK inhibitor treatment.

Nearly isocaloric time-restricted eating shifts circadian clocks but does not improve cardiometabolic health in women with overweight or obesity.

Viral and immune correlates of viral rebound dynamics post-ART were identified in an animal model of pediatric HIV infection.

PTPN2 deletion or inhibition boosts CAR T cell function and promotes the formation of stem cell memory CAR T cells for persistent solid tumor control.

Computers built with analogue circuits promise huge speed and efficiency gains over ordinary computers, but normally at the cost of accuracy. Now, an analogue computer designed to carry out calculations that are key to AI training could fix that

Computers built with analogue circuits promise huge speed and efficiency gains over ordinary computers, but normally at the cost of accuracy. Now, an analogue computer designed to carry out calculations that are key to AI training could fix that

During sleep, your brain cleans itself by flushing through cerebrospinal fluid to prevent damage to brain cells. If you're lacking in sleep, this happens when you are awake – and seems to cause momentary lapses in attention

During sleep, your brain cleans itself by flushing through cerebrospinal fluid to prevent damage to brain cells. If you're lacking in sleep, this happens when you are awake – and seems to cause momentary lapses in attention

Combining a quantum-inspired algorithm and quantum information processing technologies could enable researchers to measure masses of cosmic objects that bend light almost imperceptibly

Combining a quantum-inspired algorithm and quantum information processing technologies could enable researchers to measure masses of cosmic objects that bend light almost imperceptibly

The Trump administration has laid off government workers integral to major public health surveys, meaning the country will lack crucial information on births, deaths and illnesses nationwide

The Trump administration has laid off government workers integral to major public health surveys, meaning the country will lack crucial information on births, deaths and illnesses nationwide

Plague, leprosy, smallpox and other diseases didn't jump from animals to humans when we thought. Ancient DNA is revealing where they come from and how they changed history

Plague, leprosy, smallpox and other diseases didn't jump from animals to humans when we thought. Ancient DNA is revealing where they come from and how they changed history

The monster hurricane pummelling Jamaica is powered by abnormal sea surface temperatures in the Caribbean, which were made at least 500 times more likely by global warming

The monster hurricane pummelling Jamaica is powered by abnormal sea surface temperatures in the Caribbean, which were made at least 500 times more likely by global warming

Among over-50s, women seem to require less exercise than men to get the same reduction in heart disease risk, suggesting health guidelines need to be updated

Among over-50s, women seem to require less exercise than men to get the same reduction in heart disease risk, suggesting health guidelines need to be updated