There are a host of celestial events to get excited about next year – including a total solar eclipse. Abigail Beall is lining up her calendar

Scientist and photographer Felice Frankel has zoomed in on everyday occurrences with her camera for her new book, Phenomenal Moments, which reveals the hidden science in our daily lives

Neuroscience columnist Helen Thomson on how she discovered a host of evidence-based ways to keep her brain healthier in 2026

Feedback has spent some time sifting through 2025's key scientific achievements to come up with a range of weird and wonderful (and less wonderful) winners for our inaugural Backsies awards

Scientist and photographer Felice Frankel has zoomed in on everyday occurrences with her camera for her new book, Phenomenal Moments, which reveals the hidden science in our daily lives

Neuroscience columnist Helen Thomson on how she discovered a host of evidence-based ways to keep her brain healthier in 2026

Feedback has spent some time sifting through 2025's key scientific achievements to come up with a range of weird and wonderful (and less wonderful) winners for our inaugural Backsies awards

Our gut microbiome has a huge influence on our overall health, but we haven't been clear on the specific bacteria with good versus bad effects. Now, a study of more than 34,000 people is shedding light on what a healthy gut microbiome actually consists of

Our gut microbiome has a huge influence on our overall health, but we haven't been clear on the specific bacteria with good versus bad effects. Now, a study of more than 34,000 people is shedding light on what a healthy gut microbiome actually consists of

From a particle smasher encircling the moon to an “impossible” laser, five scientists reveal the experiments they would run in a world powered purely by imagination

From a particle smasher encircling the moon to an “impossible” laser, five scientists reveal the experiments they would run in a world powered purely by imagination

The rollout of a type of genetic technology called a gene drive for tackling malaria could be edging closer after a lab study supports its success

The rollout of a type of genetic technology called a gene drive for tackling malaria could be edging closer after a lab study supports its success

An excavation in Suffolk, UK, has uncovered pyrite and flint that appear to have been used by ancient humans to light fires some 400,000 years ago

An excavation in Suffolk, UK, has uncovered pyrite and flint that appear to have been used by ancient humans to light fires some 400,000 years ago

In the Research Article “Impairment of stromal-epithelial regenerative cross-talk in Hirschsprung disease primes for the progression to enterocolitis” by Z. Zhang et al., there were inadvertent image duplications in Figs. 4F, 6F, and S7. In Fig. 4F, the Lgr5 smFISH staining of 3-week wild-type and Ednrb−/− mouse colon was inadvertently duplicated from the 2-week group shown in Fig. 3H. In Fig. 6F, the 40× image for HSCR colostomy rectum stained for PDGFRα/MMP1/DAPI did not match the corresponding 10× image. In fig. S7, the image representing HSCR-derived organoids on day 0 was incorrect and duplicated from the images shown in Fig. 7J. Figures 4F and 6F and fig. S7 have been updated with the correct images. The other data and the conclusions in the paper are not affected.

Antigen-agnostic isolation of B cells enabled the AI-assisted identification of broadly neutralizing antibodies targeting OPG153.

ZAP327 CAR T cells outperform conventional CAR T cells in antitumor efficacy and safety by increasing the memory cell population.

Alternative splicing resulting in STAT3 that lacks a single amino acid, S701, increases colonic inflammation and tumorigenesis.

Infants from a traditional farming community exhibited antibody profiles that were found to be associated with lower incidence of egg allergy.