Partial repair of cardiac right vagus nerve using an implantable conduit after vagal resection limits cardiac tissue damage and dysfunction.

ATR/PKMYT1 coinhibition induces synthetic lethality in Rb1-deficient breast cancers, supporting biomarker-guided therapy.

Bacteria-targeted tuftsin–presenting nanoparticles stimulate the macrophage Fcγ receptor to improve antimicrobial defenses in sepsis.

HDAC5 governs wound repair by deacetylating cytosolic ACTN4, and the selective activator G194-0712 improves chronic wound healing in mouse models.

Epileptic network analysis based on fast ripple interregional coincidence allows us to identify brain targets for neurostimulation treatment.

Systemic immune profiling of individuals with asymptomatic or symptomatic dengue reveals distinct transcriptional patterns.

Naturally occurring genetic variants in genes encoding human target antigens can confer resistance to antibody-based therapies.

An orally active positive allosteric modulator of the human Mas-related G protein–coupled receptor X1 is a potential therapy for neuropathic pain.

PIEZO1 restoration protects against tyrosine kinase inhibitor–induced endothelial dysfunction, hypertension, and cardiac injury.

Engineered dendritic cells called iCAR-DCs integrate tumor-antigen uptake with programmable cell activation in mouse cancer models.

Gedatolisib is more effective than alpelisib in preclinical models of PIK3CA-mutant ER+ advanced breast cancer.

In the Research Article “Impairment of stromal-epithelial regenerative cross-talk in Hirschsprung disease primes for the progression to enterocolitis” by Z. Zhang et al., there were inadvertent image duplications in Figs. 4F, 6F, and S7. In Fig. 4F, the Lgr5 smFISH staining of 3-week wild-type and Ednrb−/− mouse colon was inadvertently duplicated from the 2-week group shown in Fig. 3H. In Fig. 6F, the 40× image for HSCR colostomy rectum stained for PDGFRα/MMP1/DAPI did not match the corresponding 10× image. In fig. S7, the image representing HSCR-derived organoids on day 0 was incorrect and duplicated from the images shown in Fig. 7J. Figures 4F and 6F and fig. S7 have been updated with the correct images. The other data and the conclusions in the paper are not affected.

Antigen-agnostic isolation of B cells enabled the AI-assisted identification of broadly neutralizing antibodies targeting OPG153.

ZAP327 CAR T cells outperform conventional CAR T cells in antitumor efficacy and safety by increasing the memory cell population.

Alternative splicing resulting in STAT3 that lacks a single amino acid, S701, increases colonic inflammation and tumorigenesis.

Infants from a traditional farming community exhibited antibody profiles that were found to be associated with lower incidence of egg allergy.

Clinical phenotypes are modestly associated with distinct channel dysfunctions caused by 42 CACNA1A de novo variants.

Preclinical models of SARS-CoV-2 vaccination revealed a targetable CXCL10–IFN-γ axis that drives cytokine-induced cardiac injury.

A mineralized collagen scaffold activates Gli1 expression and supports fibrocartilage repair in preclinical enthesis injury.

A vaccine candidate induces antibodies that inhibit the ability of IgE antibodies to bind their receptor on granulocytes (Conde et al., this issue).