Science
Impaired TIM4-mediated efferocytosis by liver macrophages contributes to fibrosis in metabolic dysfunction–associated steatohepatitis | Science Translational Medicine
Restoring TIM4 in liver macrophages in MASH improves the efferocytosis of apoptotic hepatocytes, which dampens the progression to liver fibrosis.
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A soft robotic device for rapid and self-guided intubation | Science Translational Medicine
A soft robotic device autonomously and rapidly guides intubation in models and cadavers and requires minimal skill and no visualization.
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Human myelinated brain organoids with integrated microglia as a model for myelin repair and remyelinating therapies | Science Translational Medicine
Human myelinated brain organoids with integrated microglia can be used to investigate demyelination, remyelination, and remyelinating therapies.
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Type I interferon limits central nervous system autoimmunity by modulating the microRNA-21–FOXO1 axis in pathogenic T helper 17 cells | Science Translational Medicine
Type I interferon limits central nervous system autoimmunity by regulating microRNA-21 and pathogenic T helper 17 cell development.
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Interferon-induced senescent CD8+ T cells reduce anti-PD1 immunotherapy efficacy in early triple-negative breast cancer | Science Translational Medicine
Interferon-induced senescent CD8+ T cells mediate immunotherapy nonresponsiveness in early TNBC, which can be reversed by nicotinamide mononucleotide.
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Iridescent mammals are much more common than we thought
It has long been claimed that only one mammal – the golden mole – has fur that shimmers with rainbow colours, but it now turns out that at least a dozen more mammals have iridescent fur too
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Iridescent mammals are much more common than we thought
It has long been claimed that only one mammal – the golden mole – has fur that shimmers with rainbow colours, but it now turns out that at least a dozen more mammals have iridescent fur too
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‘Great Migration’ involves far fewer wildebeest than we had thought
An estimate that as many as 1.3 million wildebeest move across the Serengeti Mara landscape each year has been cut down to size using AI
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‘Great Migration’ involves far fewer wildebeest than we had thought
An estimate that as many as 1.3 million wildebeest move across the Serengeti Mara landscape each year has been cut down to size using AI
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How cosmic events may have influenced hominin evolution
Some cosmic events could have profoundly altered the lives of our ancient human relatives. Did Neanderthals go extinct, at least in part, due to changes in Earth’s magnetic field? Did Australopithecus witness huge meteorite impacts?
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How cosmic events may have influenced hominin evolution
Some cosmic events could have profoundly altered the lives of our ancient human relatives. Did Neanderthals go extinct, at least in part, due to changes in Earth’s magnetic field? Did Australopithecus witness huge meteorite impacts?
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Is Earth’s climate in a state of 'termination shock'?
Cleaning up air pollution has saved millions of lives, but it has also given us an inadvertent taste of a nightmare climate scenario. The race is on to understand how bad it could be – and how to swerve the worst effects
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Is Earth’s climate in a state of 'termination shock'?
Cleaning up air pollution has saved millions of lives, but it has also given us an inadvertent taste of a nightmare climate scenario. The race is on to understand how bad it could be – and how to swerve the worst effects
Categories: Science
Geoengineering is not going to save the poles from climate change
A review of the five main methods proposed for cooling down the poles or slowing the loss of ice concludes they are all wildly impractical, wouldn't work, or both
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Geoengineering is not going to save the poles from climate change
A review of the five main methods proposed for cooling down the poles or slowing the loss of ice concludes they are all wildly impractical, wouldn't work, or both
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Can a strange new treatment finally relieve chronic sinus infections?
Constant loss of smell, facial pain and a blocked nose are a reality for the 10 per cent of people living with chronic rhinosinusitis, a disease long-neglected by research. Targeting the nasal microbiome, though, is offering hope
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Can a strange new treatment finally relieve chronic sinus infections?
Constant loss of smell, facial pain and a blocked nose are a reality for the 10 per cent of people living with chronic rhinosinusitis, a disease long-neglected by research. Targeting the nasal microbiome, though, is offering hope
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Resistance training may strengthen your gut microbiome
People who made the greatest gains in muscle power over eight weeks of resistance training also improved the balance of bacteria in their gut
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Resistance training may strengthen your gut microbiome
People who made the greatest gains in muscle power over eight weeks of resistance training also improved the balance of bacteria in their gut
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No, AI isn’t going to kill us all, despite what this new book says
The arguments made by AI safety researchers Eliezer Yudkowsky and Nate Soares in If Anyone Builds It, Everyone Dies are superficially appealing but fatally flawed, says Jacob Aron
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