Science

Impaired TIM4-mediated efferocytosis by liver macrophages contributes to fibrosis in metabolic dysfunction–associated steatohepatitis | Science Translational Medicine

Restoring TIM4 in liver macrophages in MASH improves the efferocytosis of apoptotic hepatocytes, which dampens the progression to liver fibrosis.
Categories: Science

A soft robotic device for rapid and self-guided intubation | Science Translational Medicine

A soft robotic device autonomously and rapidly guides intubation in models and cadavers and requires minimal skill and no visualization.
Categories: Science

Human myelinated brain organoids with integrated microglia as a model for myelin repair and remyelinating therapies | Science Translational Medicine

Human myelinated brain organoids with integrated microglia can be used to investigate demyelination, remyelination, and remyelinating therapies.
Categories: Science

Type I interferon limits central nervous system autoimmunity by modulating the microRNA-21–FOXO1 axis in pathogenic T helper 17 cells | Science Translational Medicine

Type I interferon limits central nervous system autoimmunity by regulating microRNA-21 and pathogenic T helper 17 cell development.
Categories: Science

Interferon-induced senescent CD8+ T cells reduce anti-PD1 immunotherapy efficacy in early triple-negative breast cancer | Science Translational Medicine

Interferon-induced senescent CD8+ T cells mediate immunotherapy nonresponsiveness in early TNBC, which can be reversed by nicotinamide mononucleotide.
Categories: Science

Iridescent mammals are much more common than we thought

New Scientist - Space - Wed, 10/09/2025 - 03:01
It has long been claimed that only one mammal – the golden mole – has fur that shimmers with rainbow colours, but it now turns out that at least a dozen more mammals have iridescent fur too
Categories: Science

Iridescent mammals are much more common than we thought

New Scientist - Technology - Wed, 10/09/2025 - 03:01
It has long been claimed that only one mammal – the golden mole – has fur that shimmers with rainbow colours, but it now turns out that at least a dozen more mammals have iridescent fur too
Categories: Science

‘Great Migration’ involves far fewer wildebeest than we had thought

New Scientist - Space - Tue, 09/09/2025 - 22:21
An estimate that as many as 1.3 million wildebeest move across the Serengeti Mara landscape each year has been cut down to size using AI
Categories: Science

‘Great Migration’ involves far fewer wildebeest than we had thought

New Scientist - Technology - Tue, 09/09/2025 - 22:21
An estimate that as many as 1.3 million wildebeest move across the Serengeti Mara landscape each year has been cut down to size using AI
Categories: Science

How cosmic events may have influenced hominin evolution

New Scientist - Space - Tue, 09/09/2025 - 21:00
Some cosmic events could have profoundly altered the lives of our ancient human relatives. Did Neanderthals go extinct, at least in part, due to changes in Earth’s magnetic field? Did Australopithecus witness huge meteorite impacts?
Categories: Science

How cosmic events may have influenced hominin evolution

New Scientist - Technology - Tue, 09/09/2025 - 21:00
Some cosmic events could have profoundly altered the lives of our ancient human relatives. Did Neanderthals go extinct, at least in part, due to changes in Earth’s magnetic field? Did Australopithecus witness huge meteorite impacts?
Categories: Science

Is Earth’s climate in a state of 'termination shock'?

New Scientist - Space - Tue, 09/09/2025 - 19:00
Cleaning up air pollution has saved millions of lives, but it has also given us an inadvertent taste of a nightmare climate scenario. The race is on to understand how bad it could be – and how to swerve the worst effects
Categories: Science

Is Earth’s climate in a state of 'termination shock'?

New Scientist - Technology - Tue, 09/09/2025 - 19:00
Cleaning up air pollution has saved millions of lives, but it has also given us an inadvertent taste of a nightmare climate scenario. The race is on to understand how bad it could be – and how to swerve the worst effects
Categories: Science

Geoengineering is not going to save the poles from climate change

New Scientist - Space - Tue, 09/09/2025 - 13:00
A review of the five main methods proposed for cooling down the poles or slowing the loss of ice concludes they are all wildly impractical, wouldn't work, or both
Categories: Science

Geoengineering is not going to save the poles from climate change

New Scientist - Technology - Tue, 09/09/2025 - 13:00
A review of the five main methods proposed for cooling down the poles or slowing the loss of ice concludes they are all wildly impractical, wouldn't work, or both
Categories: Science

Can a strange new treatment finally relieve chronic sinus infections?

New Scientist - Space - Mon, 08/09/2025 - 21:00
Constant loss of smell, facial pain and a blocked nose are a reality for the 10 per cent of people living with chronic rhinosinusitis, a disease long-neglected by research. Targeting the nasal microbiome, though, is offering hope
Categories: Science

Can a strange new treatment finally relieve chronic sinus infections?

New Scientist - Technology - Mon, 08/09/2025 - 21:00
Constant loss of smell, facial pain and a blocked nose are a reality for the 10 per cent of people living with chronic rhinosinusitis, a disease long-neglected by research. Targeting the nasal microbiome, though, is offering hope
Categories: Science

Resistance training may strengthen your gut microbiome

New Scientist - Space - Mon, 08/09/2025 - 21:00
People who made the greatest gains in muscle power over eight weeks of resistance training also improved the balance of bacteria in their gut
Categories: Science

Resistance training may strengthen your gut microbiome

New Scientist - Technology - Mon, 08/09/2025 - 21:00
People who made the greatest gains in muscle power over eight weeks of resistance training also improved the balance of bacteria in their gut
Categories: Science

No, AI isn’t going to kill us all, despite what this new book says

New Scientist - Space - Mon, 08/09/2025 - 20:09
The arguments made by AI safety researchers Eliezer Yudkowsky and Nate Soares in If Anyone Builds It, Everyone Dies are superficially appealing but fatally flawed, says Jacob Aron
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