A prototype cell partly capable of replicating itself has been created using 36 existing bacterial genes, but it's not really a living organism – yet

A prototype cell partly capable of replicating itself has been created using 36 existing bacterial genes, but it's not really a living organism – yet

Aya Koda's Tree is an account of the late writer's visits to Japan's most famous, and ancient, trees. Featured in Wim Wenders's film Perfect Days, it is original and thought-provoking, says Rowan Hooper

Aya Koda's Tree is an account of the late writer's visits to Japan's most famous, and ancient, trees. Featured in Wim Wenders's film Perfect Days, it is original and thought-provoking, says Rowan Hooper

The vibrant colours and delicate details of New Zealand's fungi and slime moulds are documented in these images, taken from Jay Lichter's new book The Secret Life of Fungi

Feedback is informed of an exciting new development in underwear design from a brand that says it infuses its products with beneficial bacteria to nourish the skin microbiome

The vibrant colours and delicate details of New Zealand's fungi and slime moulds are documented in these images, taken from Jay Lichter's new book The Secret Life of Fungi

Feedback is informed of an exciting new development in underwear design from a brand that says it infuses its products with beneficial bacteria to nourish the skin microbiome

Just a few weeks after one of the most unusual government interventions in the AI industry, Claude Fable 5 is making its return.

A philosopher has put forward an argument for rethinking how particles are defined within the standard model of particle physics

A philosopher has put forward an argument for rethinking how particles are defined within the standard model of particle physics

A form of fibre that boosts the release of the hunger-reducing hormone GLP-1 has been approved as safe by a European regulator, and could be added to foods within a year

A form of fibre that boosts the release of the hunger-reducing hormone GLP-1 has been approved as safe by a European regulator, and could be added to foods within a year

In the Research Article “Guanosine diphosphate–mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer” by Ding et al., duplication errors occurred between Fig. 3C and Fig. 5D and between fig. S3C and Fig. 2F. The blot for alpha-tubulin in Fig. 3C and colony images in fig. S3C have been corrected. The mislabeled concentrations in fig. S3C have been corrected. The online versions of Fig. 3C, the Supplementary Materials, and data files S1 and S2 have been updated. The corrections did not affect the conclusions of the paper.

Neurotensin is an endogenous inhibitor of adverse cardiac remodeling.

A CALR mutant–targeted CAR T cell therapy selectively depletes mutant CALR+ cancer stem cells in vivo and in fibrotic human bone marrow organoids.

Targeting the HIF-1α/PI3Kδ/IL-13 axis in chronic GVHD skin alleviates IL-13–driven hypoxia and subsequent fibrosis.

The integration of large-scale proteomic and genetic data identified 18 Alzheimer’s disease risk genes acting through regulation of blood proteins.

A microneedle stent enables intestinal anastomosis and localized drug delivery for postoperative adjuvant therapy in resectable intestinal diseases.

KS-PDX models demonstrate expansion of KSHV-infected endothelial cells with up-regulated angiogenic signaling pathways and CXCR4 expression.