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Erratum for the Research Article “Extracellular vesicle–mediated gene editing for the treatment of nonsyndromic progressive hearing loss in adult mice” | Science Translational Medicine
In the Research Article “Extracellular vesicle–mediated gene editing for the treatment of nonsyndromic progressive hearing loss in adult mice” by X. Pan et al., a competing interest was not disclosed in the initially published version. The following sentence was added the “Competing interests” section of the Acknowledgments: “M.H. has a financial interest in ExoDel, Inc., a company that options technology evaluated in this research and that could benefit from the results of the research.”
Categories: Science
Keratin 16 inhibits type I interferon responses in differentiating keratinocytes of stressed and diseased skin | Science Translational Medicine
Keratin 16 suppresses type I interferon and innate immunity in the skin, offering insight into diseases such as pachyonychia congenita and psoriasis.
Categories: Science
A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology | Science Translational Medicine
A human iPSC–derived tauopathy model endogenously recapitulates late-stage pathology and enables translational applications.
Categories: Science
Pharmacological activation of WASp potentiates macrophage phagocytosis and enhances ibrutinib efficacy against mouse models of brain tumors | Science Translational Medicine
Activating macrophage phagocytosis with a WASp activator augments ibrutinib efficacy against primary and metastatic brain tumors.
Categories: Science
Design of a neutralizing and protective pan–encephalitic alphavirus receptor decoy protein | Science Translational Medicine
An engineered protein receptor decoy protects mice from lethal infection caused by three antigenically distinct encephalitic alphaviruses.
Categories: Science
Corticosteroid resistance is predetermined by early immune response dynamics at acute graft-versus-host disease onset | Science Translational Medicine
Steroid-resistant acute graft-versus-host disease is set at disease onset and leads to distinct cell-to-cell cross-talk and immune trajectories.
Categories: Science
Real-time intraocular pressure monitoring and responsive drug release in preclinical models by an all-polymer smart contact lens | Science Translational Medicine
Battery- and electronics-free theranostic contact lens tracks IOP and autonomously delivers drugs, enabling low-cost, personalized glaucoma care.
Categories: Science
Particles seen emerging from empty space for first time
By tracing the origins of an unusual, short-lived particle, researchers have gathered some of the strongest evidence yet that mass can emerge from fluctuations in the vacuum
Categories: Science
Particles seen emerging from empty space for first time
By tracing the origins of an unusual, short-lived particle, researchers have gathered some of the strongest evidence yet that mass can emerge from fluctuations in the vacuum
Categories: Science
Why The Double Helix is such an extraordinary but infuriating book
James Watson’s The Double Helix is probably one of the greatest science books of all time – but Michael Le Page finds he can’t recommend that anyone actually reads it
Categories: Science
Why The Double Helix is such an extraordinary but infuriating book
James Watson’s The Double Helix is probably one of the greatest science books of all time – but Michael Le Page finds he can’t recommend that anyone actually reads it
Categories: Science
How a century-long argument over light’s true nature came to an end
Two of the forefathers of quantum theory, Albert Einstein and Niels Bohr, had a famous argument over whether light is a wave or a particle. Columnist Karmela Padavic-Callaghan finds that the matter has been settled once and for all
Categories: Science
How a century-long argument over light’s true nature came to an end
Two of the forefathers of quantum theory, Albert Einstein and Niels Bohr, had a famous argument over whether light is a wave or a particle. Columnist Karmela Padavic-Callaghan finds that the matter has been settled once and for all
Categories: Science
The most stunning pictures from Artemis II’s flyby of the moon
The crew of NASA’s Artemis II mission have captured extraordinary views of the moon, including close-ups of the far side and a breathtaking solar eclipse
Categories: Science
The most stunning pictures from Artemis II’s flyby of the moon
The crew of NASA’s Artemis II mission have captured extraordinary views of the moon, including close-ups of the far side and a breathtaking solar eclipse
Categories: Science
I don’t see images in my head. Can training give me a mind’s eye?
Training programmes for people with aphantasia – the inability to create mental images – are challenging neuroscientists' understanding of how we create thoughts
Categories: Science
I don’t see images in my head. Can training give me a mind’s eye?
Training programmes for people with aphantasia – the inability to create mental images – are challenging neuroscientists' understanding of how we create thoughts
Categories: Science
Migraines could be treated by ramping up the brain's cleaning system
Amplifying the brain's waste disposal system seems to clear a substance that drives migraines, relieving some of the pain associated with the condition
Categories: Science
Migraines could be treated by ramping up the brain's cleaning system
Amplifying the brain's waste disposal system seems to clear a substance that drives migraines, relieving some of the pain associated with the condition
Categories: Science
Are manure digesters a real solution to dairy farm emissions?
Anaerobic digesters converting manure to biogas reduce methane emissions from livestock, but incentives for them have encouraged factory farms to get bigger
Categories: Science