The impact that carved out the South Pole-Aitken basin on the moon appears to have come from the north, not the south as previously thought – and NASA’s upcoming mission could investigate further

The impact that carved out the South Pole-Aitken basin on the moon appears to have come from the north, not the south as previously thought – and NASA’s upcoming mission could investigate further

Older men are more likely to pass on disease-causing mutations to their children because of the faster growth of mutant cells in the testes with age

Older men are more likely to pass on disease-causing mutations to their children because of the faster growth of mutant cells in the testes with age

Immunologist Daniel Davis wants to eradicate long-held myths and replace them with wonder at the complexity of the body’s defence system

Immunologist Daniel Davis wants to eradicate long-held myths and replace them with wonder at the complexity of the body’s defence system

Multiomics on serial glioblastoma biopsies can enable differentiation of pseudoprogression from true tumor progression (see Ling et al.).

In Sarm1-deficient mice, peripheral nervous system regeneration is delayed after injury.

Multiomic analyses of longitudinally collected human glioblastoma samples reveal evolution of the tumor microenvironment in response to therapy.

LION-delivered replicating RNA vaccines are immunogenic and protect cynomolgus macaques against lethal influenza A (H5N1) virus challenge.

Single-cell immunoprofiling uncovered systemic immune cell signatures of neurological MOG antibody–associated disease.

The FMRP-ASCC3 axis regulates collided ribosomes, and ASCC3 is reduced in fragile X syndrome, suggesting an alternative approach to treat the disease.

A biocompatible extracellular matrix hydrogel serves as a barrier to protect surgically injured tissue, limiting preclinical postoperative adhesions.

Susumu Kitagawa, Richard Robson and Omar Yaghi have been honoured for the development of metal-organic frameworks, porous materials that can capture water or pollutants

Susumu Kitagawa, Richard Robson and Omar Yaghi have been honoured for the development of metal-organic frameworks, porous materials that can capture water or pollutants

Scientists have identified five sleep profiles, each of which is linked to distinct mental health symptoms and brain activity patterns

Scientists have identified five sleep profiles, each of which is linked to distinct mental health symptoms and brain activity patterns

According to the equations that govern black holes, the larger one of these cosmic behemoths is the lower its average density – given that the universe contains a lot of relatively empty space, could the whole cosmos be a black hole?

According to the equations that govern black holes, the larger one of these cosmic behemoths is the lower its average density – given that the universe contains a lot of relatively empty space, could the whole cosmos be a black hole?

For decades, forest, grasslands and other land ecosystems have collectively absorbed up to a third of the carbon dioxide we emit each year - but this climate buffer may be collapsing far sooner than anyone expected