SETD2 methylates SRSF2 mutants and inhibits aberrant CEACAM1 splicing and IL-1β–driven inflammation in myelodysplastic syndrome.

A foldamer ligand demonstrates drug-like properties and rescues synucleinopathy disease phenotypes in multiple in vitro and in vivo models.

Resilient and sensitive microneedle biosensor longitudinally tracks pharmacokinetics in skin and detects early signs of preclinical organ dysfunction.

B cell responses that bound to future H1N1 and influenza B virus strains, but not H3N2 strains, were elicited in adults by the 1994 influenza vaccine.

BAP1, LSD1, and PARP1 roles in nucleotide excision repair are revealed; BAP1-mutant pancancers are sensitive to LSD1i SP2509/2577 and PARPi olaparib.

A virus seems to have jumped from marine animals into people for the first time ever, and it is causing serious vision problems

A virus seems to have jumped from marine animals into people for the first time ever, and it is causing serious vision problems

Plug-in solar panels are a cheaper, simpler alternative to professionally installed panels. But can they really reduce energy bills and are they safe? Matthew Sparkes investigates

Plug-in solar panels are a cheaper, simpler alternative to professionally installed panels. But can they really reduce energy bills and are they safe? Matthew Sparkes investigates

A study based on tree rings claimed that droughts played a role in events that led to the Roman withdrawal from Britain, but other researchers say that isn't backed up by historical evidence

A study based on tree rings claimed that droughts played a role in events that led to the Roman withdrawal from Britain, but other researchers say that isn't backed up by historical evidence

A collection of stories set in George R. R. Martin’s Wild Cards universe and a novel from The Expanse author James S. A. Corey are among the science-fiction books we’re looking forward to this month

A collection of stories set in George R. R. Martin’s Wild Cards universe and a novel from The Expanse author James S. A. Corey are among the science-fiction books we’re looking forward to this month

The muon collider was once dismissed as impossible, but is now gaining steam as the successor to the Large Hadron Collider. If built, it could offer a new window to reality 

The muon collider was once dismissed as impossible, but is now gaining steam as the successor to the Large Hadron Collider. If built, it could offer a new window to reality 

The immune system going rogue and attacking healthy tissue seems to behind some cases of long covid, a discovery that could open doors towards treatments

The immune system going rogue and attacking healthy tissue seems to behind some cases of long covid, a discovery that could open doors towards treatments

Improved hardware can send ten times as much data through existing fibre-optic cables, potentially providing a way to massively upgrade the internet's infrastructure without the cost and inconvenience of laying any new cables

Improved hardware can send ten times as much data through existing fibre-optic cables, potentially providing a way to massively upgrade the internet's infrastructure without the cost and inconvenience of laying any new cables

The science suggests that olive oil can help us fight cognitive decline and even Alzheimer’s. Columnist Helen Thomson finds that only works if we choose the right kind