A noninvasive, noncontrast, clinically viable technique assesses myocardial oxygen dynamics.

An oral prodrug of the neurosteroid drug allopregnanolone shows enhanced bioavailability while retaining pharmacology in a clinical trial.

The zinc finger–mediated repression of SCN9A in pain-sensing neurons lasts up to 6 months and has a favorable safety profile in nonhuman primates.

De-repressing SEC23A transcription via LSD1 inhibition or deletion of the SEC23A promoter sequence occupied by LSD1 compensates for SEC23B deficiency.

Researchers have re-analysed a set of elephant bones and a wooden spear found in Germany in 1948, which provide compelling evidence of Neanderthals' big game hunting abilities

Researchers have re-analysed a set of elephant bones and a wooden spear found in Germany in 1948, which provide compelling evidence of Neanderthals' big game hunting abilities

Fifty years ago, Richard Dawkins shared an irresistible scientific metaphor with the world that modernised and democratised evolutionary biology. Half a century on, The Selfish Gene remains powerfully insightful, finds Rowan Hooper

Fifty years ago, Richard Dawkins shared an irresistible scientific metaphor with the world that modernised and democratised evolutionary biology. Half a century on, The Selfish Gene remains powerfully insightful, finds Rowan Hooper

A start-up has worked out how to preserve the brain after death – paving the way for immortality in a distant future. But beginning to reckon with this reality yields serious practical and philosophical questions

A start-up has worked out how to preserve the brain after death – paving the way for immortality in a distant future. But beginning to reckon with this reality yields serious practical and philosophical questions

One in 10 homes tested in the UK, Italy and the Netherlands have dangerous levels of benzene because of slow leaks from gas hobs and ovens

One in 10 homes tested in the UK, Italy and the Netherlands have dangerous levels of benzene because of slow leaks from gas hobs and ovens

Our solar system’s rocky planets – Mercury, Venus, Earth and Mars – may have formed from two rings around the young sun, rather than a single disc

Our solar system’s rocky planets – Mercury, Venus, Earth and Mars – may have formed from two rings around the young sun, rather than a single disc

Infections are increasingly being linked to a higher risk of dementia. In the latest research, scientists have found that being treated in hospital for a severe infection seems to raise the risk of developing the condition over the next five to six years

Infections are increasingly being linked to a higher risk of dementia. In the latest research, scientists have found that being treated in hospital for a severe infection seems to raise the risk of developing the condition over the next five to six years

We've always thought that Tyrannosaurus rex was an unchallenged apex predator during the dying days of the dinosaurs. But a fresh look at controversial fossils has prompted palaeontology’s biggest-ever U-turn

We've always thought that Tyrannosaurus rex was an unchallenged apex predator during the dying days of the dinosaurs. But a fresh look at controversial fossils has prompted palaeontology’s biggest-ever U-turn

CERN is working on building an antimatter delivery service. The project passed a big test by successfully transporting 92 antiprotons around a 4-kilometre loop of road

CERN is working on building an antimatter delivery service. The project passed a big test by successfully transporting 92 antiprotons around a 4-kilometre loop of road