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Epigenetically regulated pancreatic GABA-somatostatin signaling underlies gestational diabetes–induced glucose intolerance in offspring | Science Translational Medicine
TET-controlled GABA-somatostatin signaling in pancreatic islets underlies intrauterine hyperglycemia-induced glucose intolerance in offspring.
Categories: Science
Drug screening on tumor organoids exposes therapeutic vulnerabilities of meningiomas to HDAC1/2i panobinostat | Science Translational Medicine
The HDAC inhibitor panobinostat is effective against aggressive meningiomas, and resistance is mediated through a targetable HDAC8-TGFβ-EMT axis.
Categories: Science
Engineering CAR T cells to secrete VEGF-neutralizing scFvs enhances antitumor activity against solid tumors | Science Translational Medicine
Armoring CAR T cells with the ability to secrete VEGF-neutralizing single-chain variable fragments enhances potency and control of tumors in vivo.
Categories: Science
Cell-free DNA fragmentomes for noninvasive detection of liver cirrhosis and other diseases | Science Translational Medicine
Genome-wide cfDNA fragmentomes are altered in liver disease and other morbidities and enable noninvasive detection of liver fibrosis and cirrhosis.
Categories: Science
Claude AI: Why are there so many internet outages?
AI chatbot Claude going down is just one example of a recent IT outage. One of the main vulnerabilities of the modern internet is to blame for the growing number of incidents
Categories: Science
Claude AI: Why are there so many internet outages?
AI chatbot Claude going down is just one example of a recent IT outage. One of the main vulnerabilities of the modern internet is to blame for the growing number of incidents
Categories: Science
How worried should you be about microplastics?
Microplastics have been found accumulating everywhere from our water to our body tissues, but many of the claims have come under fresh scrutiny. Chelsea Whyte cuts through the research to tell you whether you really need to worry
Categories: Science
How worried should you be about microplastics?
Microplastics have been found accumulating everywhere from our water to our body tissues, but many of the claims have come under fresh scrutiny. Chelsea Whyte cuts through the research to tell you whether you really need to worry
Categories: Science
Phantom codes could help quantum computers avoid errors
A method for making quantum computers less error-prone could let them run complex programs such as simulations of materials more efficiently, thus making them more useful
Categories: Science
Phantom codes could help quantum computers avoid errors
A method for making quantum computers less error-prone could let them run complex programs such as simulations of materials more efficiently, thus making them more useful
Categories: Science
Rare family has had many more sons than daughters for generations
Analysing the births of a Utah family over seven generations has revealed that their disproportionate number of boys could be caused by a selfish Y chromosome
Categories: Science
Rare family has had many more sons than daughters for generations
Analysing the births of a Utah family over seven generations has revealed that their disproportionate number of boys could be caused by a selfish Y chromosome
Categories: Science
Your microbiome may determine your risk of a severe allergic reaction
The microbes that live in our mouth and gut may influence whether an allergic reaction to peanuts is mild or life-threatening, and could be harnessed to ward off a severe attack
Categories: Science
Your microbiome may determine your risk of a severe allergic reaction
The microbes that live in our mouth and gut may influence whether an allergic reaction to peanuts is mild or life-threatening, and could be harnessed to ward off a severe attack
Categories: Science
10 Most Secure Email Service Providers for Personal Use
If you are searching for the most secure email service, you are really asking one question: Who can read your email messages?
Why the US is using a cheap Iranian drone against the country itself
The US and Iran are trading blows in the Gulf with a simple drone that costs as little as $50,000 to make. But why is a slow, cheap and relatively primitive drone seeing use in 2026 alongside hypersonic missiles and stealth jets?
Categories: Science
Why the US is using a cheap Iranian drone against the country itself
The US and Iran are trading blows in the Gulf with a simple drone that costs as little as $50,000 to make. But why is a slow, cheap and relatively primitive drone seeing use in 2026 alongside hypersonic missiles and stealth jets?
Categories: Science
Can Michael Pollan crack the problem of consciousness in his new book?
The science writer delves into the vast subject of consciousness in his new book A World Appears – and draws some surprising conclusions, finds Grace Wade
Categories: Science
Can Michael Pollan crack the problem of consciousness in his new book?
The science writer delves into the vast subject of consciousness in his new book A World Appears – and draws some surprising conclusions, finds Grace Wade
Categories: Science
Would aliens do physics, or is science a human invention?
Shaped by a different biology or culture, other intelligent civilisations – if they’re out there – might understand the universe in a completely different way than we do. Physicist Daniel Whiteson explores what that could tell us about physics and ourselves
Categories: Science