Antigen-specific and functionally stable Treg cells can be generated in vitro from effector/memory T cells for cell therapy of inflammatory diseases.

Functionally stable regulatory T cells converted in vitro from pathogenic T cells can confer antigen-specific immunosuppression in pemphigus vulgaris.

LRG1-driven microvascular dysfunction triggers early diabetic retinopathy, highlighting a potential therapeutic target.

HIVEP1 drives ODC1 expression and polyamine metabolism in liver TH17 cells to promote NAFLD-to-NASH progression.

The microbes that take hold in our bodies during early life have long-term effects on our brain health. Helen Thomson investigates how to get kids’ microbiomes off to the best start.

The microbes that take hold in our bodies during early life have long-term effects on our brain health. Helen Thomson investigates how to get kids’ microbiomes off to the best start.

Antidepressants can be very effective, but they also come with side effects that vary from one drug to the next, supporting the idea of more personalised prescriptions

Antidepressants can be very effective, but they also come with side effects that vary from one drug to the next, supporting the idea of more personalised prescriptions

An exclusive New Scientist survey of leading scientists reveals widespread concern that schemes to tweak Earth’s atmosphere could launch within decades in a risky bid to cool the planet

An exclusive New Scientist survey of leading scientists reveals widespread concern that schemes to tweak Earth’s atmosphere could launch within decades in a risky bid to cool the planet

Confining and rotating extremely cold atoms or molecules within atomic “Ferris wheels” made from laser light could test relativity’s predictions on the quantum scale

Confining and rotating extremely cold atoms or molecules within atomic “Ferris wheels” made from laser light could test relativity’s predictions on the quantum scale

We have more satellites than ever before, but when they burn up they create a new kind of air pollution. Evidence is now revealing what effects this could have and how to tackle it

We have more satellites than ever before, but when they burn up they create a new kind of air pollution. Evidence is now revealing what effects this could have and how to tackle it

The comet-like object Chiron has been caught in the process of forming new rings, which could help us understand how these complex systems work

The comet-like object Chiron has been caught in the process of forming new rings, which could help us understand how these complex systems work

Many of the signs of perimenopause can also be symptoms of other conditions, and some of these get increasingly dangerous if they’re misdiagnosed

Many of the signs of perimenopause can also be symptoms of other conditions, and some of these get increasingly dangerous if they’re misdiagnosed

Breastfeeding seems to cause specialised immune cells to flood into the breasts and stay there for years or even decades, reducing the risk of cancer

Breastfeeding seems to cause specialised immune cells to flood into the breasts and stay there for years or even decades, reducing the risk of cancer