KRAS G12D and G12C produce lung tumors with distinct microenvironmental and growth features that influence progression and survival.

The E205D point mutation in the key detoxification gene CYP6P3 increases insecticide resistance in the malaria vector Anopheles gambiae.

Disrupting the SREBP-1–glucose uptake feedforward loop sensitizes tumors to lysosome inhibition–based therapy.

METRNL is elevated in candidemia in mice and humans and provides a potential therapeutic target for life-threatening candidemia.

Skin temperature modulation and hypothalamic thermosensitivity dissociate REM sleep and cataplexy, independent of brain and core body temperatures.

A first-in-class compound targeting the oncogene AVIL demonstrated efficacy and safety in mouse models of glioblastoma.

CSF1R-targeted crystals preserve xenogeneic cell function in mice and allogeneic cell function in NHPs but fail to maintain xenogeneic cells in NHPs.

In the Report “APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia” by G. Sienski et al., an error during the revision process resulted in two microscopy images, E3/E3 choline and E4/E4 vehicle, from Fig. 4D being incorrectly duplicated in Fig. 1E. The microscopy images in Fig. 1E have now been corrected, and the conclusions and other data in the paper are not affected.

A swine and human study shows that treating multidrug-resistant Pseudomonas aeruginosa pneumonia with inhaled high-dose nitric oxide is safe.

Newborn screen metabolites encapsulate the risk for adverse outcomes of prematurity through a deep learning–based metabolic health index.

CAR T cells generated in vivo by T cell–targeted mRNA-LNP delivery eliminated scar-forming cells and ameliorated fibrosis in steatotic liver disease.

Integrated multiome analysis identifies loss of PPARG2 as a driver of liposarcoma dedifferentiation and GLP-1 signaling as a targetable program.

The histamine receptor H3 antagonist bavisant promotes neuroprotection and remyelination in cell and mouse models of multiple sclerosis.

In the Research Article “Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice” by J. Ramos da Silva et al., the image for the day 21 gDE7 U sa-mRNA-LNP group in Fig. 6B was erroneously duplicated in Fig. 6G. The day 21 gDE7 U sa-mRNA-LNP image in Fig. 6G has been updated with the correct image. The other data and conclusions in the manuscript were not affected.

Brain-derived tau in plasma reflects the extent of brain injury in acute ischemic stroke, predicts functional outcomes, and detects treatment effects.

An antibody cocktail targeting conserved epitopes on the RSV A and B pre-F protein prevents viral escape and confers prophylactic protection in vivo.

Soluble CD93 contributes to podocyte injury, and CD93 blockade emerges as a candidate therapeutic target in INS.

Brigatinib enhances PARPi response in HGSOC by disrupting adaptive survival of malignant cells by dual FAK and EPHA2 inhibition.

FACT and BET inhibition in diffuse midline glioma drives tumor suppression and immune modulation, highlighting a dual therapeutic strategy.

In the Research Article “Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair” by K. Mylonas et al., an inadvertent image duplication affected Fig. 3C. An immunofluorescent image of collagen I staining and quantification was presented correctly in Fig. 6I alongside a graph quantifying collagen I staining in young nonirradiated versus young irradiated kidneys, but it was accidentally duplicated and shown incorrectly accompanying a different graph of young versus aged kidney collagen I staining in Fig. 3C. Figure 3C has been replaced with a corrected image. The other data and the conclusions in the paper are not affected.